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简要描述:3011 Coelenterazine-SOL in vivo说明Nanolight®Technology是一家生物技术公司,开发天然,发光海洋蛋白或海洋生物发光的广泛应用。 Nanolight部门致力于成为制药,农业和研究产物行业新产物开发的高价值试剂和报告系统的。有价值的生命科学用于狈补苍辞濒颈驳丑迟®的技术包括高通量药物发现,功能基因组学,肿瘤成像,放射性同位素替代和分子诊断
3011 Coelenterazine-SOL in vivo说明
苏州蚂蚁淘生物科技有限公司是狈补苍辞濒颈驳丑迟品牌特约代理商,提供狈补苍辞濒颈驳丑迟所有产物,质量保证,货号型号齐
狈补苍辞濒颈驳丑迟&谤别驳;罢别肠丑苍辞濒辞驳测是一家生物技术公司,开发天然,发光海洋蛋白或海洋生物发光的广泛应用。&苍产蝉辫;狈补苍辞濒颈驳丑迟部门致力于成为制药,农业和研究产物行业新产物开发的高价值试剂和报告系统的。
有价值的生命科学用于狈补苍辞濒颈驳丑迟&谤别驳;的技术包括高通量药物发现,功能基因组学,肿瘤成像,放射性同位素替代和分子诊断
Nanolight品牌3011 Coelenterazine-SOL in vivo中英文说明书
3011 Coelenterazine-SOL in vivo说明
Native Coelenterazine formulated to be water-soluble and safe for in vivo imaging applications with Gaussia Luciferase.
Coelenterazine is often dissolved in Propyleneglycol (PG) in combination with other alcohols for in vivo imaging studies. Large intravenous doses of PG given over a short period of time can be toxic, including hyperosmolality, increased anion gap metabolic acidosis (due to lactic acidosis), acute kidney injury, and sepsis-like syndrome.
This can be avoided using water-soluble Coelenterazine. It is formulated to be isosmotic and easily secreted by the kidneys. Thus save for repeated i.v. injections. Water-soluble Coelenterazine can be injected up to a 500 µg/100 µl concentration, achieving very high Coelenterazine levels within the body and leADIng to high Gaussia luciferase signals.
?Content: | ?native Coelenterazine + non-toxic additives for water-solublity |
Packaging size: | ?500 ug CTZ / vial in a freeze-dried form |
?Storage: | sealed vials can be stored at: -80°C for long-term storage -20°C for short-term storage Store dry and dark! |
?Application: | ?just add sterile water, vortex and use up to 500 ug CTZ in a single injection |
Application example: |
A detailed describtion of this new water soluble Coelenterazine can be found in:
A Water-Soluble Coelenterazine for Sensitive In Vivo Imaging of Coelenterate Luciferases. Danielle Morse and Bakhos A Tannous |
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